This medication is known as a diuretic (like a "water pill"). It helps your body get rid of extra water by increasing the amount of urine you make. Getting rid of extra water decreases the strain on your heart and blood vessels, thereby lowering high blood pressure and reducing your risk of strokes, heart attacks, and kidney problems. This effect can also improve symptoms such as trouble breathing and swelling (edema). This injectable form of furosemide is used when the drug cannot be taken by mouth, especially in patients with severe medical conditions. OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This medication can also be used to decrease calcium in the blood (hypercalcemia).

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Effects of d-tubocurarine, flaxedil and quaternary ammonium derivatives of stilbene on various functions of the sympathetic nervous system APX in the glyoxysomal membrane can work in cooperation with monodehydroascorbate reductase to oxidize NADH, regenerate ascorbate, detoxify H(2)O(2), and protect the integrity of glyoxysomal proteins and membranes. Resumption of heartbeat in dogs after standstill at low temperatures. One patient in the MST-cisapride group developed acute pancreatitis.

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Substrate specificity and kinetic framework of a DNAzyme with an expanded chemical repertoire: a putative RNaseA mimic that catalyzes RNA hydrolysis independent of a divalent metal cation. Continuous exposure of Mongolian gerbils to perchloroethylene (PCE) (120 ppm) for 12 months in an inhalation chamber caused no changes in body or brain weights. Although several scenarios can result in a lack of concordance between historical patterns and contemporary experiments, we argue that the coupling of phylogenetic and experimental methods is an increasingly revealing approach to hypothesis testing in evolutionary ecology. These results indicate that diabetes-induced vascular hypertrophy and remodeling is associated with reexpression of embryonic forms of FN and myosin heavy chain.

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A structured evaluation was performed at enrollment and again at a 5- to 7-day follow-up visit. Endodermal cyst of the cervical spinal cord with associated partial fusion of the vertebrae.

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Inhibiting the phosphorylation of the p38 mitogen-activated protein kinase without modifying JNK, neither diminishes cell death nor inhibits NP1 overexpression in nondepolarizing conditions. The regulatory pathways controlling cell cycle phases include several oncogenes and tumor suppressor genes that display a range of abnormalities with potential usefulness as markers of evolution or treatment response in ovarian cancer. Mosquito adulticidal activity of a biosurfactant produced by Bacillus subtilis subsp.

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These characteristics make Ras proteins with nonprotein fluorophores suitable for biophysical analysis. Using double labeling, we determined whether Wnt2, Wnt7a, and GSK-3beta were colocalized with beta-tubulin III, for neurons, or glial fibrillary acidic protein, for mature astrocytes.

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The quenching ability of Gd(III) was stronger towards the radicals provided by HA than by HY, what was assigned to higher content in HA of both, oxygen-containing functional groups and conjugated aromatic rings, leading to more efficient Gd(III)-radical interaction. Cast-brace treatment for fractures of the distal part of the femur. The findings indicate a clearer understanding of bacteremia emerging in the past 30 years, which has led to recent changes in antibiotic prophylaxis regimens. To compare 2 urethral stricture models and determine the appropriate model for the generation of urethral stricture in rabbits. Some CGRP-like fibers were also recognized in the outer zone of the median eminence.

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Comparison of effects of various brands of ACTH on normal subjects. The structural and enzymatic components of retroviral cores are formed by proteolytic cleavage of precursor polypeptides, mediated by the viral protease (PR). In 10- and 20-day-old rats, in addition to the above areas, IGF-I immunoreactivity was also observed in capillary walls, ependymal cells, choroid plexus, glial cells and most fiber paths.

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Sensory reweighting of proprioceptive information of the left and right leg during human balance control. Blue emitting gold nanoclusters templated by poly-cytosine DNA at low pH and poly-adenine DNA at neutral pH. Verbal selective learning after traumatic brain injury in children. There was no evidence for overall attentional deficits in people at risk for affective disorders.

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This chapter gives an overview of the potential adverse effects in relation to prenatal gene therapy and describes the techniques that can be used experimentally in a large animal model to monitor the potential adverse consequences of prenatal gene therapy, with relevance to clinical application. It has been found that the lens wet weight increased progressively with the stage of maturation of cataract, i.e., from mature to hypermature which was significant and also with increase in age.

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Subunit structure and gene control of mouse NADP-malate dehydrogenase. As a powerful tool to analyse microstructural evolution under irradiation and the interaction of moving dislocations with radiation-induced defects, a focused ion beam (FIB) method was applied to ion-irradiated SiC followed by the nano-indentation test.

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Symmetrical and asymmetrical synaptic contacts were observed on somata and dendrites of labelled neurons, the latter being more frequent. It also provides a flexible definition of futility that is patient centered and reliant on goals of care as the morally preferable definition.

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Since the immortalized lymphoid cell lines neither form colonies in soft agar medium nor induce tumors after injection into immunodeficient nude mice, we suggest that these cytokines may be involved in autocrine growth stimulation of human lymphoid cell lines immortalized by transfection with cytoplasmic DNA from mouse L-cells. Plasma and blood transfusion in the treatment of infectious nonspecific polyarthritis in children It is emerging that the influence of the gut microbiota also extends to modulation of host neural development.

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Activation of an alpha-fetoprotein (AFP)/receptor autocrine loop in HT-29 human colon carcinoma cells. Thus, the histidines in the first group (His-367, -372, -551) were crucial for 5-lipoxygenase activity, possibly because of a function of these residues as metal ligands. All 5 tumors had 1 or more genetic mutations in the genes examined. The peak-to-peak time (tau(pp)) of the laser (1064 nm) induced pressure transient was used to estimate the axial vessel diameter. Previously vague terms could be clearly defined when they are broken down into their constituent parts.

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The rate of phospholipid turnover in brain subcellular fractions differ from that in the liver tissue. The results indicated that the inter-tissue method using an air signal provided good accuracy and was consistent with signal detectability using observer performance. Antibody-morpholinodoxorubicin conjugates were prepared for targeted immunotherapy of human melanoma. Like patients with relapsing remitting or secondary progressive multiple sclerosis, PPMS patients may be at risk of an autoimmune response during IFNB treatment. One set of HBC cells expressed identical requirements for IN and EGF in primary culture as normal cells.

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The effects of suppression of CD44 by CD44-specific antisense oligonucleotide on attachment of human trabecular meshwork cells to hyaluronic acid (HA) were observed and the possible relationship between CD44 and primary open-angle glaucoma (POAG) investigated. The characteristics of the brain activity in these patients were evaluated from the late positive component of the cerebral evoked potential in response to painful stimuli (pain-related P250).

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Problems are viewed as falling into several major categories: administration, personnel, location, space allocation, structural, layout, and undue reliance on generalized formulas. Efficacy of valproate maintenance in patients with bipolar disorder and alcoholism: a double-blind placebo-controlled study. The impact of shortened assay turnaround times with point-of-care technology on length of stay in the emergency department has been limited to date, with most randomized evaluations of this technology having demonstrated little or no reduction in this outcome parameter.

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In cases with status epilepticus, edema and neuronal degeneration was observed in the hippocampus, amygdala, thalamic nuclei of the midline, entorhinal cortex, and cerebellum. We suppose that specific scenarios of transcription initiation are essentially related to various particular implementations of the interaction of basal transcription machinery with promoter DNA, depending on the presence and mutual positioning of core promoter elements. Evaluating short health training courses through content analysis. The information obtained from AS-EAST will help to design experimental analyses for the functional significance of novel splice isoforms. These results helped to reveal health risk factors for workers engaged into chromium ores extraction and for nearby residents.

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Purified Rgg also bound to the promoter regions of emm49, sof, and sfbX49 in vitro. These diseases are characterized by the production of high levels of immunoglobulin E in response to common allergens. They also showed an improvement in the use of leisure time and a trend towards improvement in motivation. In both the presence and absence of serum, 3Y1 rat fibroblastic cells synchronized at early S phase by aphidicolin entered M phase 6 h after removal of aphidicolin. While the expression of both CXCR1 mRNA and protein could be demonstrated by RT-PCR and FACS analysis in human Caco-2 and HT-29 cells, no expression of CXCR2 was observed in these cell lines.

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Arteriovenous endogenous cocarboxylases and alcoholemia in man in health and liver disease RNA responsible for conferring a DNase I sensitive structure on albumin gene in assembled chromatin The authors review all of the literature on this subject and compare their results with those of other authors. Hungarian patients undergo lung transplantation within bilateral cooperation in Vienna, Austria since 1995.

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Temperature and biological soil effects on the survival of selected foodborne pathogens on a mortar surface. However, the complexity of these pathways and the wide patterns of expression and activity displayed by some of their components immediately suggest additional morphogenetic roles beyond the control of CE. Effects of cortisol on cardiac myocytes and on expression of cardiac genes in fetal sheep.

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Photochemical preparation and conformational analysis by proton magnetic resonance of penicillin (R)-sulfoxides. The effects of cercarial concentration and length of exposure on the infection of mice by Schistosoma japonicum and S. Control measures of schistosomiasis in the hilly and mountain regions of Pingguo County Most reports have used techniques developed for the measurement of strain and strain rate in the adult heart and produced conflicting descriptions of gestational changes in strain.

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Effects of simultaneous or previous infusion of sugars on the utilization of infused amino acids and peptides. Similar deficits have been described in depression, but comparative studies have brought mixed results. Results of histology, microradiography and polychrome sequence labeling Radioactive carbon dioxide production from pyruvate and lactate by the preimplantation rabbit embryo.

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The stato-dynamic fraction reflects a steady change in the grip force when the same load is moved cyclically. At heel strike, an extensor response was observed at the ankle and the knee which would allow one to stabilize and plant the ipsilateral foot fast. The severity of Minamata disease declined in 25 years: temporal profile of the neurological findings analyzed by multiple logistic regression model. Most probably this breath number is more related to the severity of impaired gas mixing than to the degree of emphysema.

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Syndromes of estrogenic hyperactivity in 2 cases of primary ovarian cancers These guidelines provide information about the optimal endocrine management of male-to-female and female-to-male transsexual persons. MC3T3 cells were plated on machined, acid-etched, or acid-etched grade 4 titanium enriched with calcium phosphate, or machined, anodized, or anodized and calcium phosphate-enriched grade 5 titanium disks. Ophthalmic examinations with emphasis on color vision and electrophysiology.

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Usually MLL present like huge pedunculated mass and appear like sarcoma hence called Pseudosarcoma. A total of 944 patients underwent RARP as monotherapy for PCa from January 2002 to December 2006 at Karolinska University Hospital, Stockholm, Sweden. Following an increase in the dose from 60 to 80 mg for the second course, no sign of saturation of thio-TEPA elimination processes or of formation of the metabolite TEPA occurred, indicating dose-independent pharmacokinetics. Characterization of a Euglena gene encoding a polyprotein precursor to the light-harvesting chlorophyll a/b-binding protein of photosystem II.

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Internalization of renal type IIc Na-Pi cotransporter in response to a high-phosphate diet. There have been significant advances in the treatment of both nonsevere and severe malaria with the advent of artemisinin combination therapies and parenteral artesunate, but the optimum supportive management of severe malaria is unclear. Effects of low-power laser irradiation on cell locomotion in protozoa.

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Each patient received a single dose of desmopressin (0.3 micrograms/kg) or saline placebo intravenously at the initiation of a reconstructive surgical procedure. From 111 dogs with neurological signs admitted in this research in a 22-month period, brain samples of 34 animals were inoculated in mice in order to isolate Toxoplasma gondii. The results of complex examination and treatment of 175 patients with obturative jaundice of different genesis were analyzed Especial attention have been devoted to interaction of specific enzymes: aminotransferases, alkali phosphatase and gamma-glutamiletranspeptidase.

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Renal lesions: controlled comparison between CT and 1.5-T MR imaging with nonenhanced and gadolinium-enhanced fat-suppressed spin-echo and breath-hold FLASH techniques. Comparison of the ganglioside content of nine normal spinal cords and nine spinal cords from clinically diagnosed amyotrophic lateral sclerosis (ALS) patients revealed no major quantitative differences, but the unique presence of three additional gangliosides in ALS spinal cords. Adjusted relative risks (RRs) were calculated using Mantel-Haenszel weights and Cox proportional hazards. Characteristics of the limb malformations induced by maternal exposure to cadmium in the mouse. The designation senile systemic amyloidosis is proposed for this disease, which differs from other systemic amyloidoses in distribution of amyloid deposits.

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On the effect of the active principle and extract of fructus gardeniae on the bile secretion of rabbits, blood bilirubin and peripheral lymph bilirubin of common bile-duct ligated rabbits. Here we determined the effects of relaxin with or without beta-estradiol on the modulation of MMPs in joint fibrocartilaginous explants, and assessed the contribution of these proteinases to the loss of collagen and glycosaminoglycan (GAG) in this tissue. From these results, we suggest that this 23-kDa antigen is a marker of strain virulence upon which a virulence classification of T.

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A patient of cerebral amoebiasis due to Entamoeba histolytica with no evidence of disease elsewhere is described. By contrast to the general depression in the acquisition and expression of associative learning observed under amphetamine, the 0.5 mg/kg dose promoted the acquisition of anticipatory responses made later in the trace interval (in Experiment 2 but, again, not the expression of previous conditioning in Experiment 1b). Lengthening of the generation cycle during embryonic differentiation of the mouse neural tube. Because GAD67 and reelin are downregulated in schizophrenia, it is suggested that schizophrenics may express GABAergic deficit-related alterations of pyramidal neuron function. Assessment of the diagnostic sensitivity and specificity of an indirect ELISA kit for the diagnosis of Brucella ovis infection in rams.

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In vivo assessment of intact parathyroid hormone adsorption by different dialysis membranes during hemodialysis. To construct the aptasensor, a well-known ATP binding aptamer (ABA) splits into two segments. Construction, characterization, and complementation of Rhodospirillum rubrum puf region mutants.

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Favourable effect of lacrimal plugs after 3 and 9 months in 20 patients with severe sicca syndrome Morphological changes following previous immunization with and daily injections of phytohemagglutinin. Early versus late feeding of low birth weight neonates--a controlled study. Changes in permeability of articular cartilage in experimental lathyrism. These results show that the KHM-5M cells derived from an undifferentiated thyroid carcinoma produce multicytokines and suggest that those cytokines modified some pathological features in this case.

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GABAA receptor partially mediated propofol-induced hyperalgesia at superspinal level and analgesia at spinal cord level in rats. More on the relevance of animal tumor models: immunogenicity of transplantable leukemias of recent origin in syngeneic strain 2 guinea pigs. The main benefits of this approach will be the ability to correct the disorder before the onset of irreversible pathology and inducing central immune tolerance to the vector and transgene if treatment is instituted in early gestation. We present four patients with CRAO that have no emboli visible on ophthalmoscopy The first patient had no blood flow signal on CDI on a surface of 2 millimeters behind the optic disc.

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These findings plus previous work suggest that plasma membrane-associated Mo1 alpha is needed for a normal interaction between neutrophils and underlying surfaces, and raise the possibility that the increase in surface adhesiveness of neutrophils that have discharged their specific granules might be due in part to the increase in the amount of Mo1 alpha in the plasma membranes of these degranulated cells. These emerging fields may benefit from what has been learned from HSC assays: most important, that the true potential of stem cells can only be assessed retrospectively. An interpretation of the surface response in somatosensory cortex to peripheral and interaneal afferent stimulation. Fibroblast secreted proteins participate in the formation of extracellular matrix.