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Dutasteride, a synthetic 4-azasteroid, is a selective and competitive inhibitor of both type 1 and type 2 5-alpha-reductase isoenzymes approved for the treatment of men with symptomatic benign prostatic hyperplasia (BPH) who have an enlarged prostate. It has been demonstrated to be effective as monotherapy, or in combination with the alpha-adrenergic antagonist (α-blocker), tamsulosin, in several randomized, double-blind, placebo controlled trials and their open-label extensions. Treatment with Dutasteride is generally safe and well tolerated. Dutasteride has become established in the management of men with lower urinary tract symptoms (LUTS) and reduces the risk of acute urinary retention and surgery related to BPH. Dutasteride may also have a role as a chemopreventive agent in the future as emerging evidence demonstrates a reduced risk of prostate cancer with this agent.

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Dutasteride, Deetor, Duodart, Duprost, Dutagen, Dutas, Dutasterida, Dute, Veltride,

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The convert phase microscope was used to analyse the number and the length of neurites, as well as the maximum diameter of hippocampal neurons soma. Reduced opioid use in the immediate postoperative period is associated with decreased complications.

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The effects of diethyl ether on PaCO2 in dogs with and without vagal, somatic and sympathetic block. Insulin-like growth factor-II and basic fibroblast growth factor affect periodontal ligament cells expressing osteoprotegerin in vitro Indeed, the dendritic surfaces of pyramidal cells (the most common neuron in the cerebral cortex) are covered by thin protrusions named dendritic spines. This article reviews the incidence, diagnosis, and etiology of secondary central nervous system tumors in the setting of a history of primary pediatric malignancy. Aldehyde Dehydrogenases in Arabidopsis thaliana: Biochemical Requirements, Metabolic Pathways, and Functional Analysis.

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One recent randomized trial in adults demonstrated no benefit of the procedure and an additional randomized trial in adults is underway. Cellular immunotherapy using specific antigen-presenting cells (APCs), to overcome aspects of immune incompetence in MM patients, has received great attention, and numerous clinical trials have evaluated the potential for dendritic cell (DC) vaccines as a novel immunotherapeutic approach. Our results suggest that during sensory guided movements, sensory inputs relevant to successful completion of the movement may have access to motor systems controlling the muscles involved.

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Protective effects of phenolic alkaloids from Menispermum dauricum on inflammatory injury following focal cerebral ischemia-reperfusion in rats Using a combination of avidin-biotin microELISA and solid phase radioimmunoassay, we examined sera from 23 patients with systemic lupus erythematosus (SLE), two patients with established sensitivity to ingested shrimp, and 15 healthy normal subjects. Mouth and jaw forming apparatus for children from 2 to 10 years of age Blood pigment: physiological functions and certain pathological syndromes

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A position statement formulated by the Committee on Psychiatry and Social Work, Group for the Advancement of Psychiatry. The unique tyrosine residue that resides in apoLp-III was used to provide additional evidence for LPS binding interaction.

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Crusted scabies in a patient with chronic graft-versus-host disease. To investigate the expression of CD45RA and CD45RO antigens in leukemias and its implication in the diagnosis and differential diagnosis of leukemias. Moreover, the content of NO2- in the DRE group was higher than that of the groups of GE, AE, ALE.

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An arginine residue in the pore region is a key determinant of chloride dependence in cardiac pacemaker channels. Hemodynamics in closed chest cardiac compression--report of a case.

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Computed tomography of the chest revealed an irregular non-homogenous opacity involving the apical and posterior segments of superior lobe of the right lung. This is a review of current knowledge on the impact of diabetes mellitus in lung health. Evaluation of several methods of isolating salmonellae from poultry litter and animal feedstuffs.

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By incorporating the annotated information from the ELM resource, iELM provides functional details of PPIs. Expression of mRNA encoding SCF and c-kit were detected via in situ hybridization. Unfortunately, at least one third of patients on chronic dialysis have high serum P levels, with a consequent higher serum PTH levels, commonly associated with vitamin D deficiency, increased vascular calcification and the highest ratios of morbidity and mortality. The present studies were performed using primary monolayer cultures of bovine glomerulosa cells to determine whether the elevation in cytosolic calcium concentration produced by angiotensin II was accompanied by an elevation in mitochondrial calcium. The distribution and origin of substance P immunoreactive nerve fibres in the rat conjunctiva.

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Chronic exposure to zinc of furnace operators in a brass foundry. Study on relationship of soluble interleukin-2 receptors in serious hepatitis B patients and the T lymphocyte subgroup Provided that adequate image quality is achieved, contrast-enhanced multislice spiral computed tomography enables the identification and characterisation of calcified and non-calcified coronary plaques.

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A comprehensive knowledge of the relationships between genotype and environment is not only important for understanding the etiology of disease, but also for developing safe and effective treatment paradigms. On the precision of lipoprotein electrophoresis on cellulose acetate and its use in the diagnosis of hyperlipoproteinemia. In a model of human neuroblastoma (NB) cell lines persistently infected with human cytomegalovirus (HCMV) we previously showed that persistent HCMV infection is associated with an increased malignant phenotype, enhanced drug resistance, and invasive properties.

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Open-habitat chats (genera Myrmecocichla, Cercomela, Oenanthe and relative) are a morphologically and ecologically cohesive group of genera with unclear phylogenetic relationships. The method involved measurement of the intensity of light scattered at an angle of 31 degrees to the incident radiation by the sample. Anatomic principles of left and right regulated hepatectomy: technics The gene is 6310 base-pairs long and is interrupted by four introns.

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All craniocervical fusion procedures were performed using intraoperative fluoroscopic imaging and electrophysiological monitoring. In this paper, 35 Tupaia blangeri chinensises (TBCs) captured from Kunming,Yunnan province were investigated. Colonization of host tissues is a first step taken by many pathogens during the initial stages of infection. These findings support the hypothesis that neurotrophic factors, e.g., NGF, are critically involved in mediating perineural invasion of pancreatic cancer.

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Proximal row carpectomy with capitate osteochondral autograft transplantation. Renal damage in the course of treatment with antibiotics in infants

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To investigate the value of routine ileoscopy as an integral part of colonoscopy in terms of additional diagnostic information, extra time spent, and the relationship between ileoscopy rate and accumulation of colonoscopic experience. The CA3 zone, while relatively resistant, showed neuronal necrosis in relation to the lateral ventricle in animals with hydrocephalus.

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Daily college student drinking patterns across the first year of college. In this article, a rare case of nocardia farcinica infection with a solitary cerebral abscess is presented and the literature is reviewed. The activity of alkaline phosphatase and myeloperoxidase of leucocytes is much higher in normal lactation and much lower in hypogalactia. Fractionation of NCI-H441 and A549 cellular components indicated that the highest specific activity of (3)H-KL(4) was present in the 18,000g cellular fraction (which contains vesicles and lysosomes).

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Effect of diclofenac pretreatment on pain during propofol injection. Because the optimization uses the downhill simplex algorithm in a nine-dimensional search space, the number of iterations needed to find the optimum can vary dramatically. There is much controversy about its cause and effect in relation to malignant tumours.

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Several fibrosis areas were evident in group I and II but none in group III. Consistent with models derived from early behavioral neurology studies, neuroimaging studies support a central role for an amygdala-anterior paralimbic neural system in bipolar disorder, and implicate abnormalities in the development of this system in the disorder. Cattle with L-type (L-BSE) and H-type (H-BSE) atypical Bovine Spongiform encephalopathy (BSE) were identified in 2003 in Italy and France respectively before being identified in other countries worldwide. Prognosis of diabetes mellitus associated with tuberculosis after antibiotics and chemotherapy

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Mortality patterns in dairy animals under organized herd management conditions at Karnal, India. Fifty-two patients were reviewed following displaced fractures of the olecranon fixed by the tension band technique. Development of incapsulated receptors of the parietal peritoneum in human ontogenesis

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Natural and artificial radionuclides in seafoods and marine protein concentrates. Treatment of 51 pregnancies with danaparoid because of heparin intolerance. The pre-erythrocytic stages of malaria are inviting targets for vaccine development, because an effective immune response to these early stages would prevent symptomatic infections. Serum ghrelin was inversely correlated with body mass index and with glomerular filtration rate as measured by inulin clearance.

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Another light in the dark: review of a new method for the arthroscopic repair of triangular fibrocartilage complex. Crystallization and preliminary crystallographic studies of MOMP (major outer membrane protein) from Campylobacter jejuni. Previous studies have come to different conclusions about the presence of RNA in particles known variously as prosomes, proteasomes or multicatalytic proteinase (MCP).

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COPI and COPII have been shown to be involved in the formation of picornavirus-induced vesicles. So, the purpose of the study was to examine the in vivo expression of cytokines in mice in immunologically important tissue environments of mice that were subjected to AOS. Bayesian algorithms for simultaneous structure from motion estimation of multiple independently moving objects. Diabetic retinopathy is a disease based on vascular genesis that begins as microangiopathy and develops into macroangioapthy preceded by fibroproliferation changes. As a result, the evaluated behavioural parameters were dose-relatedly affected by MPEP.

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The aim of this study was to compare the effects of high pressure and hyperthermia when used separately and when combined in terms of blood and tissue absorption of oxaliplatin in a swine model of intraperitoneal chemotherapy. The effect of adrenocortical hormones alone and in combination with growth hormone on cardiac hypertrophy and blood pressure of hypophysectomized rats. A simple and rapid procedure for the determination of alpha amino-nitrogen and ammonia in urine. We propose an alternative to existing 2-dimensional SOM based methods for document analysis.

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Treatment of essential hypertension with B-alkylamines, especially dibenzyline. The pattern of Rose Bengal excretion for three patients with a satisfactory clinical course was different from that of a fourth patient with highly variable flow and persistent cholestasis. Urinary LTE 4 concentration may reflect a pathophysiological event involved in eosinophilic and noneosinophilic vasculitides. Prediction of developmental outcome using a perinatal risk inventory. Review of literature on the incidence of postpartum myocardial infarction, the possible mechanisms and its clinical implications are summarized.

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The identification of a second SLR gene expressed in stigmas suggests that loci unlinked to the S-locus may play a role in the self-incompatibility response, or in pollination in general. Acute lung injury (ALI) is a common, highly lethal acquired disorder that affects over one hundred thousand people each year and for which there are no specific therapies. Factors that influence retinal recovery and measures that can be taken by the surgeon to reduce light exposure to the retina are also discussed. T-DM1 is well tolerated and has single-agent activity in patients with HER2-positive MBC who have previously received both approved HER2-directed therapies and multiple chemotherapy agents.

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Core biopsy as a tool in planning the management of invasive breast cancer. Liquid chromatographic determination of salicylate and methyl salicylate in blood and application to a postmortem case.

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Measurement of NMR-1H-relaxation of the blood serum cannot be employed in the differential diagnosis of individual diseases. Nine patients had anatomic reconstruction of the posteromedial corner. Sociality of facial expressions in immersive virtual environments: a facial EMG study. These issues are of great interest not only for their biological implications, but also to the clinician who must understand the disease and direct therapies. Thus, we have studied the influence of chemotherapy (docetaxel) on intratumoral aromatase mRNA expression because aromatase is a key enzyme for intratumoral biosynthesis of estrogens.

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To evaluate quality of life (QOL) and psychosocial adjustment by standardized tests in well-characterized patients with steroid-sensitive nephrotic syndrome. We show here that removal of eight of these nine remaining amino acids, thereby creating a minimal GPI-attachment signal, results in apical expression of GPI-anchored human growth hormone. On the basis of this available evidence, the pneumococcal polysaccharide vaccine should currently be recommended for older adults, especially those who are residents of LTCFs. From this preliminary investigation, a relationship is suggested between fluorine concentrations in bone and aluminium levels in the system. Human choice behavior exhibits many paradoxical and challenging patterns.

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To examine the association of glutathione-S-transferase (GST) gene polymorphisms in patients with sporadic prostate cancer, in a North Indian population, as GSTs are active in detoxifying a wide variety of endogenous or exogenous carcinogens, and genetic polymorphisms of GSTM1, GSTT1 and GSTP1 have been assessed to evaluate the relative risk of various cancers. Exchange transfusion in the treatment of severe theophylline poisoning. Longer chain alcohols n-butanol, n-hexanol, n-octanol, and n-decanol also exerted the same type of effect, with the potency and efficacy increasing with lengthening of the carbon chain. It seems that a radical resection, in absence of systemic implants, might provide survival benefits in selected patients. Modification of precocious evoked auditory potential amplitudes observed in tinnitus

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